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Laboratory specialty services comprise a range of services, including, but not limited to, analytical testing services for pharmaceutical, biomedical, and other life sciences laboratories.
Compound 401 is a synthetic inhibitor of DNA-PK(IC50 0 28 M) and mTOR (IC50 5 3 M) It has no inhibition on p110 /p85 PI3K ( 100 M) and blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells
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HR2-928-D5/Grid Screen PEG/LiCl #D5, 185 ml - 0.1 M Tris pH 8.0, 1.0 M Lithium chloride, 30% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
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HR2-918-30/Natrix #30 (C6), 185 ml - 0.01 M Magnesium chloride hexahydrate, 0.05 M HEPES Sodium pH 7.0, 1.6 M Ammonium sulfate. Please note items from this supplier are non-returnable.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
BAY-3827 is a chemical probe and a potent, selective AMPK inhibitor. It prevents phosphorylation of acetyl-CoA carboxylase 1 and exhibits strong anti-proliferative activity in androgen-dependent prostate cancer cell lines. This compound demonstrates high selectivity for kinases, with IC50 values of 1.4 nM at low (10 μM ATP) and 15 nM at high (2 mM ATP) concentrations.
Potent and selective AMPK inhibitor.
Exhibits strong anti-proliferative activity in androgen-dependent prostate cancer cell lines.
Prevents phosphorylation of acetyl-CoA carboxylase 1.
Shows over 500-fold selectivity for most of 331 kinases.
IC50 values of 1.4 nM (10 μM ATP) and 15 nM (2 mM ATP).
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HR2-918-29/Natrix #29 (C5), 185 ml - 0.01 M Magnesium chloride hexahydrate, 0.05 M HEPES Sodium pH 7.0, 4.0 M Lithium chloride. Please note items from this supplier are non-returnable.
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HR2-928-D1/Grid Screen PEG/LiCl #D1, 185 ml - 0.1 M Citric acid pH 4.0, 1.0 M Lithium chloride, 30% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
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HR2-928-B1/Grid Screen PEG/LiCl #B1, 185 ml - 0.1 M Citric acid pH 4.0, 1.0 M Lithium chloride, 10% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
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SERVALYT™ 4-5 40 % (w/v) solution in water SERVALYT™ Carrier Ampholytes (40 % w/v in water). Standard quality (analytical grade) for general use in IEF. Size - 10ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42923.01
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HR2-928-B6/Grid Screen PEG/LiCl #B6, 185 ml - 0.1 M BICINE pH 9.0, 1.0 M Lithium chloride, 10% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
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